A lot of moms go from exclusively breastfeeding to pumping (due to work, etc), and after a week or two notice a decrease in milk supply. So the answer to this question is yes and no.
Pumps do not remove breastmilk as well as baby does. So even if you're only using the pump a few days a week at work, it's very possible you will notice your milk supply dropping. Pumping every 2 to 3 hours will keep your milk supply from completely drying up.
Many moms have to exclusively pump and continue to do so for the life of their breastfeeding experience. They may only get a few ounces per pumping though. An efficient breast pump and not skipping any pumpings are the key points for keeping a good milk supply.
If you have to pump, use a really good breast pump. Your local lactation consultant can advise you on this. Many times they can even be rented.
If exclusively pumping, you may have to use something to increase your milk supply. Herbs can really make a difference. For herbs to work, you usually have to use a lot of them. You will need to use it on a regular basis, not all at once. You will also need to continue to breastfeed or pump often.
A great product to use for increasing milk supply is Breastea. Drink often. You should start to see an increase in the first day or two.
By using herbs and pumping often, a decrease in milk supply will be minimal or non-existent.

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